pegvisomant

Ligand id: 7485

Name: pegvisomant

Classification
Compound class Peptide or derivative
Approved drug? Yes (FDA (2003), EMA (2008))
International Nonproprietary Names
INN number INN
7941 pegvisomant
Synonyms
B2036-PEG | Somavert®
Database Links
ChEMBL Ligand CHEMBL1201515
DrugBank Ligand DB00082
Search PubMed clinical trials pegvisomant
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Wikipedia Pegvisomant
Comments
Pegvisomant is a PEGylated 191 amino acid protein analogue of growth hormone, with antagonist action at the growth hormone receptor. The peptide sequence can be obtained via the ChEMBL link. PEGylation protects the peptide from proteolytic breakdown and extends its bioactive half-life.