panobinostat

Ligand id: 7489

Name: panobinostat

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 77.15
Molecular weight 349.18
XLogP 4.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2015))
IUPAC Name
(E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide
International Nonproprietary Names
INN number INN
8805 panobinostat
Synonyms
Farydak® | LBH-589 | LBH589
Database Links
CAS Registry No. 404950-80-7
ChEMBL Ligand CHEMBL483254
PubChem CID 6918837
RCSB PDB Ligand LBH
Search Google for chemical match using the InChIKey FPOHNWQLNRZRFC-ZHACJKMWSA-N
Search Google for chemicals with the same backbone FPOHNWQLNRZRFC
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Search UniChem for chemical match using the InChIKey FPOHNWQLNRZRFC-ZHACJKMWSA-N
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Wikipedia Panobinostat
Comments
Panobinostat is a non-selective histone deacetylase (HDAC) inhibitor [1-2].