modafinil

Ligand id: 7555

Name: modafinil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 79.37
Molecular weight 273.08
XLogP 3.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1998))
IUPAC Name
2-[di(phenyl)methylsulfinyl]acetamide
International Nonproprietary Names
INN number INN
6055 modafinil
Synonyms
Provigil®
Database Links
ChEMBL Ligand CHEMBL1373
DrugBank Ligand DB00745
GtoPdb PubChem SID 223365891
PubChem CID 4236
Search Google for chemical match using the InChIKey YFGHCGITMMYXAQ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YFGHCGITMMYXAQ
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Search UniChem for chemical match using the InChIKey YFGHCGITMMYXAQ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YFGHCGITMMYXAQ
Wikipedia Modafinil
Comments
Modafinil is a eugeroic (wakefulness-promoting) drug with a multi-faceted mechanism of action. In some jurisdictions this drug is classified as a controlled substance due to its possible addiction potential. It has been termed a 'smart' drug, a group of prescription medications, purchased illegally or used off-label, with alleged cognition-enhancing properties [1,4].