gabapentin enacarbil

Ligand id: 7560

Name: gabapentin enacarbil

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 101.93
Molecular weight 329.18
XLogP 3.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2011))
Is prodrug? Yes
Active form gabapentin
IUPAC Name
2-[1-[[1-(2-methylpropanoyloxy)ethoxycarbonylamino]methyl]cyclohexyl]acetic acid
International Nonproprietary Names
INN number INN
8611 gabapentin enacarbil
Synonyms
Horizant® | Regnite® | XP-13512
Database Links
CAS Registry No. 478296-72-9
ChEBI CHEBI:68840
ChEMBL Ligand CHEMBL1628502
PubChem CID 9883933
Search Google for chemical match using the InChIKey TZDUHAJSIBHXDL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone TZDUHAJSIBHXDL
Search PubMed clinical trials gabapentin enacarbil
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Search UniChem for chemical match using the InChIKey TZDUHAJSIBHXDL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone TZDUHAJSIBHXDL
Wikipedia Gabapentin enacarbil
Comments
Gabapentin enacarbil is a prodrug of gabapentin. It exhibits increased bioavailability compared to gabapentin.