nepafenac

Ligand id: 7564

Name: nepafenac

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 86.18
Molecular weight 254.11
XLogP 3.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2005), EMA (2008))
Is prodrug? Yes
Active form amfenac
IUPAC Name
2-[2-amino-3-(benzoyl)phenyl]acetamide
International Nonproprietary Names
INN number INN
7685 nepafenac
Synonyms
AHR-9434 | AL-6515 | Nevanac®
Database Links
CAS Registry No. 78281-72-8
ChEBI CHEBI:75922
ChEMBL Ligand CHEMBL1021
DrugBank Ligand DB06802
GtoPdb PubChem SID 223365900
PubChem CID 151075
Search Google for chemical match using the InChIKey QEFAQIPZVLVERP-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey QEFAQIPZVLVERP-UHFFFAOYSA-N
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Wikipedia Nepafenac
Comments
Nepafenac is a non-steroidal anti-inflammatory drug (NSAID).