ropivacaine

Ligand id: 7602

Name: ropivacaine

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View more information in the IUPHAR Pharmacology Education Project: ropivacaine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 32.34
Molecular weight 274.2
XLogP 3.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1996))
IUPAC Name
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
International Nonproprietary Names
INN number INN
5376 ropivacaine
Synonyms
1-propyl-2',6'-pipecoloxylidide | AL-381 | LEA-103 | Naropin® | ropivacaine hydrochloride
Database Links
CAS Registry No. 84057-95-4
ChEBI CHEBI:8890
ChEMBL Ligand CHEMBL1077896
DrugBank Ligand DB00296
PubChem CID 175805
Search Google for chemical match using the InChIKey ZKMNUMMKYBVTFN-HNNXBMFYSA-N
Search Google for chemicals with the same backbone ZKMNUMMKYBVTFN
Search PubMed clinical trials ropivacaine
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Search UniChem for chemical match using the InChIKey ZKMNUMMKYBVTFN-HNNXBMFYSA-N
Search UniChem for chemicals with the same backbone ZKMNUMMKYBVTFN
Wikipedia Ropivacaine
Comments
Ropivacaine is an amino amide local anaesthetic. We show the (S) enantiomer here, but the name can also be used to refer to the racemic mixture of optical isomers.