uramustine

Ligand id: 7621

Name: uramustine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 61.44
Molecular weight 251.02
XLogP 0.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
5-[bis(2-chloroethyl)amino]-1H-pyrimidine-2,4-dione
International Nonproprietary Names
INN number INN
1351 uramustine
Synonyms
U-8344 | Uracil Mustard®
Database Links
CAS Registry No. 66-75-1
ChEMBL Ligand CHEMBL1488
DrugBank Ligand DB00791
PubChem CID 6194
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Wikipedia Uramustine
Comments
Chemically uramustine is a derivative of nitrogen mustard and uracil. It is used clinically as a DNA alkylating anti-cancer chemotherapeutic.