AZD1332

Ligand id: 7700

Name: AZD1332

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 100.64
Molecular weight 391.13
XLogP 3.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-chloro-2-N-[1-(5-fluoropyridin-2-yl)ethyl]-4-N-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine
Synonyms
AZD 1332 | AZD-1332
Database Links
ChEMBL Ligand CHEMBL2007421
PubChem CID 49831044
Search Google for chemical match using the InChIKey LBVKEEFIPBQIMD-UHFFFAOYSA-N
Search Google for chemicals with the same backbone LBVKEEFIPBQIMD
Search UniChem for chemical match using the InChIKey LBVKEEFIPBQIMD-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone LBVKEEFIPBQIMD
Comments
AZD1332 is an inhibitor of neurotrophic tyrosine kinase receptors trkA, B and C (aka neurotrophic tyrosine kinase, receptor, type 1, 2 and 3). This compound is included in AstaZeneca's Open Innovation Pharmacology Toolbox.