AZD1656

Ligand id: 7701

Name: AZD1656

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 128.66
Molecular weight 478.2
XLogP 1.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Withdrawn drug? Yes
IUPAC Name
3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide
Synonyms
AZD 1656 | AZD-1656
Database Links
ChEMBL Ligand CHEMBL3219124
GtoPdb PubChem SID 223366034
PubChem CID 16039797
Search Google for chemical match using the InChIKey FJEJHJINOKKDCW-INIZCTEOSA-N
Search Google for chemicals with the same backbone FJEJHJINOKKDCW
Search UniChem for chemical match using the InChIKey FJEJHJINOKKDCW-INIZCTEOSA-N
Search UniChem for chemicals with the same backbone FJEJHJINOKKDCW
Comments
AZD1656 activates glucokinase (GCK; P35557). AZD1656 was developed as a potential treatment for diabetes. This compound is included in AstaZeneca's Open Innovation Pharmacology Toolbox.