AZD4547

Ligand id: 7707

Name: AZD4547

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 91.51
Molecular weight 463.26
XLogP 4.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide
Synonyms
AZD-4547 | KB-74810
Database Links
CAS Registry No. 1035270-39-3
ChEBI CHEBI:63453
GtoPdb PubChem SID 223366040
PubChem CID 51039095
RCSB PDB Ligand 66T
Search Google for chemical match using the InChIKey VRQMAABPASPXMW-HDICACEKSA-N
Search Google for chemicals with the same backbone VRQMAABPASPXMW
Search UniChem for chemical match using the InChIKey VRQMAABPASPXMW-HDICACEKSA-N
Search UniChem for chemicals with the same backbone VRQMAABPASPXMW
Comments
AZD4547 was a fibroblast growth factor receptor (FGFR) tyrosine kinase family inhibitor, investigated as a potential treatment for solid tumours. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.