AZD6495

Ligand id: 7711

Name: AZD6495

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 83.72
Molecular weight 441.2
XLogP 2.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-(4-methylpiperazin-1-yl)quinoline-3-carboxamide
Synonyms
AZD 6495 | AZD-6495
Database Links
ChEMBL Ligand CHEMBL481806
PubChem CID 16755780
Search Google for chemical match using the InChIKey IBHNEKVLDKCEQY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IBHNEKVLDKCEQY
Search UniChem for chemical match using the InChIKey IBHNEKVLDKCEQY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone IBHNEKVLDKCEQY
Comments
AZD6495 is an investigational inhibitor of the colony stimulating factor-1 receptor (CSF-1R) tyrosine kinase [1]. It was developed as an antineoplastic agent. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.