AZD7325

Ligand id: 7712

Name: AZD7325

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 90.13
Molecular weight 354.15
XLogP 3.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
Synonyms
AZD 7325 | AZD-7325
Database Links
ChEMBL Ligand CHEMBL1783282
PubChem CID 23581869
Search Google for chemical match using the InChIKey KYDURMHFWXCKMW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone KYDURMHFWXCKMW
Search UniChem for chemical match using the InChIKey KYDURMHFWXCKMW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone KYDURMHFWXCKMW
Comments
AZD7325 was developed as a positive allosteric modulator of the GABAA α2 and α3 channels and was investigated as a treatment for generalised anxiety disorder. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.