AZD8055

Ligand id: 7714

Name: AZD8055

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 93.07
Molecular weight 465.24
XLogP 2.19
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
[5-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol
Synonyms
AZD 8055 | AZD-8055
Database Links
CAS Registry No. 1009298-09-2
ChEMBL Ligand CHEMBL1801204
GtoPdb PubChem SID 223366047
PubChem CID 25262965
Search Google for chemical match using the InChIKey KVLFRAWTRWDEDF-IRXDYDNUSA-N
Search Google for chemicals with the same backbone KVLFRAWTRWDEDF
Search UniChem for chemical match using the InChIKey KVLFRAWTRWDEDF-IRXDYDNUSA-N
Search UniChem for chemicals with the same backbone KVLFRAWTRWDEDF
Comments
AZD8055 is an inhibitor of the mammalian target of rapamycin (mTOR) kinase [1]. AZD8055 was investigated as a potential treatment for various types of relapsed and/or refactory cancer. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.