AZD8329

Ligand id: 7715

Name: AZD8329

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 84.22
Molecular weight 421.24
XLogP 5.1
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[4-(2-adamantylcarbamoyl)-5-tert-butylpyrazol-1-yl]benzoic acid
Synonyms
AZD 8329 | AZD-8329
Database Links
ChEMBL Ligand CHEMBL2177609
PubChem CID 25006684
Search Google for chemical match using the InChIKey XWBXJBSVYVJAMZ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XWBXJBSVYVJAMZ
Search UniChem for chemical match using the InChIKey XWBXJBSVYVJAMZ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XWBXJBSVYVJAMZ
Comments
AZD8329 is an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This compound is included in AstaZeneca's Open Innovation Pharmacology Toolbox.