AZD8542

Ligand id: 7716

Name: AZD8542

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 69.04
Molecular weight 412.19
XLogP 5.09
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide
Synonyms
AZD 8542 | AZD-8542
Database Links
PubChem CID 53344810
Search Google for chemical match using the InChIKey SMQVBAGSZVHCJP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SMQVBAGSZVHCJP
Search UniChem for chemical match using the InChIKey SMQVBAGSZVHCJP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone SMQVBAGSZVHCJP
Comments
AZD8542 was developed as an antagonist of Smoothened (SMO), with potential as an oncology therapeutic [2]. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.