AZ12260493

Ligand id: 7725

Name: AZ12260493

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 78.1
Molecular weight 439.19
XLogP 6.35
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-tert-butyl-1,1-dioxo-5-phenyl-4-[(4-piperidin-1-ylphenyl)amino]-1,2-thiazol-3-one
Synonyms
AZ 12260493 | AZ-12260493
Database Links
PubChem CID 11655079
Search Google for chemical match using the InChIKey IVANYIPLGFVBGR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IVANYIPLGFVBGR
Search UniChem for chemical match using the InChIKey IVANYIPLGFVBGR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone IVANYIPLGFVBGR
Comments
AZ12260493 was developed as an agonist of the liver X receptors α and β and investigated as a treatment for dyslipidaemia. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.