AZD7687

Ligand id: 7827

Name: AZD7687

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 106.17
Molecular weight 367.19
XLogP 4.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Synonyms
AZD 7687 | AZD-7687
Database Links
CAS Registry No. 1166827-44-6 (source: Scifinder)
ChEMBL Ligand CHEMBL2178953
GtoPdb PubChem SID 223366158
PubChem CID 42636350
Search Google for chemical match using the InChIKey YXFNPRHZMOGREC-SHTZXODSSA-N
Search Google for chemicals with the same backbone YXFNPRHZMOGREC
Search UniChem for chemical match using the InChIKey YXFNPRHZMOGREC-SHTZXODSSA-N
Search UniChem for chemicals with the same backbone YXFNPRHZMOGREC
Comments
AZD7687 is a potent and selective inhibtor of diacylglycerol O-acyltransferase 1 (DGAT1).
This compound was in the AstraZeneca/MRC repurposing list from 2011.
PubChem CID 42636350 represents ths molecule wih no specified stereochemisrty.