delcasertib   Click here for help

GtoPdb Ligand ID: 7840

Synonyms: BMS-875944 | CS-9803 | KAI-9803
Compound class: Peptide or derivative
Comment: The synthesis of delcasertib is described in [1]. Delcasertib is a peptidic agent which is an isozyme-selective delta protein kinase C (PKCδ) inhibitor. It consists of a cargo peptide (CSFNSYELGSL) derived from the δV1-1 portion of PKCδ which acts to inhibit PKCδ translocation, conjugated to the cell-penetrating, arginine-rich peptide sequence of the HIV type 1 transactivator protein (TAT45-57 CYGRKKRRQRRR) which acts as a cellular delivery system.
Classification Click here for help
Compound class Peptide or derivative
International Nonproprietary Names Click here for help
INN number INN
9466 delcasertib
Synonyms Click here for help
BMS-875944 | CS-9803 | KAI-9803
Database Links Click here for help
GtoPdb PubChem SID 223366171
PubChem CID 56843747
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