DQP-1105

Ligand id: 7843

Name: DQP-1105

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 99.4
Molecular weight 557.1
XLogP 6.79
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[3-(4-bromophenyl)-5-(6-methyl-2-oxo-4-phenyl-3H-quinolin-3-yl)-3,4-dihydropyrazol-2-yl]-4-oxobutanoic acid
Synonyms
KB-272091
Database Links
CAS Registry No. 380560-89-4
PubChem CID 76849261
Search Google for chemical match using the InChIKey ACUGSRUCGXYFTL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ACUGSRUCGXYFTL
Search UniChem for chemical match using the InChIKey ACUGSRUCGXYFTL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ACUGSRUCGXYFTL
Comments
DQP-1105 is a negative allosteric modulator of the GluN2C/D NMDA receptor inhibiting receptor function more potently when glutamate (but not glycine) is present [1].