BV-6

Ligand id: 7914

Name: BV-6

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 18
Hydrogen bond donors 8
Rotatable bonds 37
Topological polar surface area 239.28
Molecular weight 1204.74
XLogP 15.89
No. Lipinski's rules broken 4

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-methylaminopropanoyl]amino]acetyl]-N-[(2S)-1-[6-[[(2S)-2-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-methylaminopropanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3,3-di(phenyl)propanoyl]amino]hexylamino]-1-oxo-3,3-di(phenyl)propan-2-yl]pyrrolidine-2-carboxamide
Synonyms
BV6
Database Links
CAS Registry No. 1001600-56-1
GtoPdb PubChem SID 249565597
PubChem CID 23657864
Search Google for chemical match using the InChIKey DPXJXGNXKOVBJV-YLOPQIBLSA-N
Search Google for chemicals with the same backbone DPXJXGNXKOVBJV
Search UniChem for chemical match using the InChIKey DPXJXGNXKOVBJV-YLOPQIBLSA-N
Search UniChem for chemicals with the same backbone DPXJXGNXKOVBJV
Comments
BV-6 is a bivalent SMAC mimetic which acts as a dual cIAP and XIAP inhibitor [1].