BGT-226

Ligand id: 7951

Name: BGT-226

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 73.83
Molecular weight 534.2
XLogP 4.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[5,4-c]quinolin-2-one
Synonyms
BGT 226 | BGT-226 free base | BGT226 | NPV-BGT226
Database Links
CAS Registry No. 915020-55-2
ChEMBL Ligand CHEMBL3218578
PubChem CID 11978790
Search Google for chemical match using the InChIKey BMMXYEBLEBULND-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BMMXYEBLEBULND
Search UniChem for chemical match using the InChIKey BMMXYEBLEBULND-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone BMMXYEBLEBULND
Comments
BGT-226 is a novel pan class I PI3K and mTOR inhibitor [1]. The oral formulation of BGT-226 contains its maleate salt (PubChem CID 57336745).