tabalumab   Click here for help

GtoPdb Ligand ID: 8000

Synonyms: LY 2127399 | LY2127399
Immunopharmacology Ligand
Compound class: Antibody
Comment: Tabalumab is a monoclonal antibody directed against B-cell activating factor (BAFF, TNFSF13B). It was being developed as a treatment for autoimmune diseases [1] and B cell malignancies [2].
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. Peptide sequence BLAST search using the heavy chain variable region of tabalumab provides 100% match to a sequence claimed in patent US7317089 [3], and to the antibody with designation 4A5-3.1.1-B4.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9430 tabalumab
Synonyms Click here for help
LY 2127399 | LY2127399
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 385
Other databases
GtoPdb PubChem SID 249565680
Search PubMed clinical trials tabalumab
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Wikipedia Tabalumab