BMS-214662

Ligand id: 8026

Name: BMS-214662

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 129.71
Molecular weight 489.13
XLogP 5.32
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3R)-1-(3H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile
Synonyms
BMS 214662 | BMS214662 | BVM
Database Links
CAS Registry No. 195987-41-8
ChEMBL Ligand CHEMBL351706
PubChem CID 448545
RCSB PDB Ligand BMV
Search Google for chemical match using the InChIKey OLCWFLWEHWLBTO-HSZRJFAPSA-N
Search Google for chemicals with the same backbone OLCWFLWEHWLBTO
Search UniChem for chemical match using the InChIKey OLCWFLWEHWLBTO-HSZRJFAPSA-N
Search UniChem for chemicals with the same backbone OLCWFLWEHWLBTO
Comments
BMS-214662 is a non-peptidomimetic competitive farnesyltransferase inhibitor (FTI) [2].