AZD3409

Ligand id: 8027

Name: AZD3409

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 17
Topological polar surface area 142.95
Molecular weight 574.24
XLogP 6.43
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
propan-2-yl (2S)-2-[1-[2-(2-fluoroethyl)-5-[[(2S,5S)-5-(pyridine-3-carbonylsulfanyl)pyrrolidin-2-yl]methylamino]phenyl]ethenylamino]-4-methylsulfanylbutanoate
Synonyms
AZD 3409 | AZD-3409
Database Links
GtoPdb PubChem SID 249565707
PubChem CID 56603668
Search Google for chemical match using the InChIKey GIJNHMGFNKZBIR-URORMMCBSA-N
Search Google for chemicals with the same backbone GIJNHMGFNKZBIR
Search UniChem for chemical match using the InChIKey GIJNHMGFNKZBIR-URORMMCBSA-N
Search UniChem for chemicals with the same backbone GIJNHMGFNKZBIR
Comments
AZD3409 is an an orally active double prodrug, peptidomimetic type farnesyltransferase inhibitor (FTI). It is a double prodrug in that it has its thiol and carboxylate groups blocked to reduce toxicity.