BIX 02565

Ligand id: 8039

Name: BIX 02565

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 84.19
Molecular weight 458.24
XLogP 3.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(5R)-N-[1-[3-(dimethylamino)propyl]benzimidazol-2-yl]-5-methyl-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-8-carboxamide
Synonyms
BIX-02565 | BIX02565
Database Links
CAS Registry No. 1311367-27-7
ChEMBL Ligand CHEMBL1933288
GtoPdb PubChem SID 249565719
PubChem CID 53246941
Search Google for chemical match using the InChIKey ZHMXXVNQAFCXKK-QGZVFWFLSA-N
Search Google for chemicals with the same backbone ZHMXXVNQAFCXKK
Search UniChem for chemical match using the InChIKey ZHMXXVNQAFCXKK-QGZVFWFLSA-N
Search UniChem for chemicals with the same backbone ZHMXXVNQAFCXKK
Comments
BIX 02565 [1] is an inhibitor that can be used as a tool compound to study the activity of the AGC family protein kinase RSK2. Known off-target effects have been determined against LRRK2, PRKD1/2/3 and RET kinases.