Compound class:
Synthetic organic
Comment: MI-3 inhibits the interaction between MLL oncoproteins (re-arranged lysine (K)-specific methyltransferases) and the tumour suppressor protein menin (MEN1, O00255) [1]. MI-3 represents a novel molecular mechanism with potential application in the treatment of aggressive leukemias with MLL rearrangements.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
4-[4-(5,5-dimethyl-4H-1,3-thiazol-2-yl)piperazin-1-yl]-6-propan-2-ylthieno[2,3-d]pyrimidine |
Database Links | |
CAS Registry No. | 1271738-59-0 |
GtoPdb PubChem SID | 249565783 |
PubChem CID | 51001299 |
Search Google for chemical match using the InChIKey | FUGQNAUKABUDQI-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | FUGQNAUKABUDQI |
UniChem Compound Search for chemical match using the InChIKey | FUGQNAUKABUDQI-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | FUGQNAUKABUDQI-UHFFFAOYSA-N |