compound 26 [PMID: 24673130]

Ligand id: 8134

Name: compound 26 [PMID: 24673130]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 64.69
Molecular weight 240.08
XLogP 2.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
6-(3-fluorophenyl)pyrido[3,2-d]pyrimidin-4-amine
Database Links
ChEMBL Ligand CHEMBL3262587
PubChem CID 86703914
Search Google for chemical match using the InChIKey TWTLUQDFSDYZKO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone TWTLUQDFSDYZKO
Search UniChem for chemical match using the InChIKey TWTLUQDFSDYZKO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone TWTLUQDFSDYZKO
Comments
Compound 26 is a selective inhibitor of MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4) [1].