CEP-11981

Ligand id: 8189

Name: CEP-11981

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 89.66
Molecular weight 477.23
XLogP 2.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Synonyms
CEP 11981 | CEP11981 | compound 11b [PMID 22148921]
Database Links
BindingDB Ligand 50379186
ChEMBL Ligand CHEMBL2010872
PubChem CID 11751922
Search Google for chemical match using the InChIKey AEULIVPVIDOLIN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone AEULIVPVIDOLIN
Search UniChem for chemical match using the InChIKey AEULIVPVIDOLIN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone AEULIVPVIDOLIN
Comments
CEP-11981 is reported as a novel oncology therapeutic agent targeting the pro-angiogenic actions of receptor tyrosine kinases such as the VEGFRs, FGFR1 and TIE-2 [1].