CM-352

Ligand id: 8259

Name: CM-352

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 142.21
Molecular weight 487.18
XLogP 2.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2R)-N-hydroxy-2-{4-[4-(methylcarbamoyl)phenoxy]benzenesulfonyl}-8-azaspiro[4.5]decane-2-carboxamide
Synonyms
compound 2 [PMID 25686022] [2]
Database Links
PubChem CID 91623362
Search Google for chemical match using the InChIKey ZUZGJCNWNOCKEB-XMMPIXPASA-N
Search Google for chemicals with the same backbone ZUZGJCNWNOCKEB
Search UniChem for chemical match using the InChIKey ZUZGJCNWNOCKEB-XMMPIXPASA-N
Search UniChem for chemicals with the same backbone ZUZGJCNWNOCKEB
Comments
CM-352 is an optimized matrix metalloproteinase (MMP) inhibitor which inhibits fibrinolysis, and represents a novel type of antihaemorrhagic agent [2].
PubChem CID 72720906 represents the molecule without the stereochemistry attributed in [2].