cenersen

Ligand id: 8270

Name: cenersen

Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Synthetic organic
International Nonproprietary Names
INN number INN
8843 cenersen
Synonyms
Aezea® (proposed proprietary name) | EL625
Database Links
Search PubMed clinical trials cenersen
Search PubMed titles cenersen
Search PubMed titles/abstracts cenersen
Comments
Cenersen is a 20mer phosphorothioate antisense oligonucleotide complementary to a region of p53 messenger RNA [1]. The oligonucleotide sequence is reported as 5′-d[P-Thio](ccctgctccc ccctggctcc)-3′ [1]. This sequence matches nucleotides 1273-1292 of RefSeq nucleotide NM_000546 (Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA).