cenersen   Click here for help

GtoPdb Ligand ID: 8270

Synonyms: Aezea® (proposed proprietary name) | EL625
Compound class: Synthetic organic
Comment: Cenersen is a 20mer phosphorothioate antisense oligonucleotide complementary to a region of p53 messenger RNA [1]. The oligonucleotide sequence is reported as 5′-d[P-Thio](ccctgctccc ccctggctcc)-3′ [1]. This sequence matches nucleotides 1273-1292 of RefSeq nucleotide NM_000546 (Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA).
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Classification Click here for help
Compound class Synthetic organic
International Nonproprietary Names Click here for help
INN number INN
8843 cenersen
Synonyms Click here for help
Aezea® (proposed proprietary name) | EL625
Database Links Click here for help
GtoPdb PubChem SID 252166482
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