chlorpromazine

Ligand id: 83

Name: chlorpromazine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 31.78
Molecular weight 318.1
XLogP 4.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name
3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
International Nonproprietary Names
INN number INN
183 chlorpromazine
Synonyms
chlorpromazine HCl | Largactil® | Thorazine®
Database Links
BindingDB Ligand 50001888
CAS Registry No. 50-53-3
ChEBI CHEBI:3647
ChEMBL Ligand CHEMBL71
DrugBank Ligand DB00477
NURSA Ligand 10.1621/KVEDIV62XD
PubChem CID 2726
RCSB PDB Ligand Z80
Search Google for chemical match using the InChIKey ZPEIMTDSQAKGNT-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZPEIMTDSQAKGNT
Search PubMed clinical trials chlorpromazine
Search PubMed titles chlorpromazine
Search PubMed titles/abstracts chlorpromazine
Search UniChem for chemical match using the InChIKey ZPEIMTDSQAKGNT-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZPEIMTDSQAKGNT
Wikipedia Chlorpromazine
Comments
Chlorpromazine was the first antipsychotic drug to be discovered. It is one of the most sedating of the typical antipsychotics and also causes antimuscarinic effects.