tucidinostat

Ligand id: 8305

Name: tucidinostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 97.11
Molecular weight 390.15
XLogP 3.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
N-(2-amino-5-fluorophenyl)-4-{[3-(pyridin-3-yl)prop-2-enamido]methyl}benzamide
International Nonproprietary Names
INN number INN
10318 tucidinostat
Synonyms
chidamide | CS-055 | CS055 | HBI-8000
Database Links
CAS Registry No. 743420-02-2
GtoPdb PubChem SID 252166517
PubChem CID 53394037
Search Google for chemical match using the InChIKey WXHHICFWKXDFOW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WXHHICFWKXDFOW
Search PubMed clinical trials tucidinostat
Search PubMed titles tucidinostat
Search PubMed titles/abstracts tucidinostat
Search UniChem for chemical match using the InChIKey WXHHICFWKXDFOW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WXHHICFWKXDFOW
Comments
Tucidinostat (chidamide) is an inhibitor of histone deacetylase (HDAC) enzymes [3]. Note that we show this compound with no specified stereochemistry.