EPZ005687

Ligand id: 8387

Name: EPZ005687

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 88.49
Molecular weight 539.29
XLogP 5.24
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-cyclopentyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[4-(morpholin-4-ylmethyl)phenyl]indazole-4-carboxamide
Synonyms
EPZ 005687 | EPZ-005687
Database Links
CAS Registry No. 1396772-26-1
PubChem CID 60160561
Search Google for chemical match using the InChIKey ZOIBZSZLMJDVDQ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZOIBZSZLMJDVDQ
Search UniChem for chemical match using the InChIKey ZOIBZSZLMJDVDQ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZOIBZSZLMJDVDQ
Comments
EPZ005687 is an inhibitor of the histone methyltransferase, enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2) [1].