DZNep

Ligand id: 8392

Name: DZNep

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 117.42
Molecular weight 264.12
XLogP -0.77
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)cyclopentane-1,2-diol
Synonyms
3-deazaneplanocin A
Database Links
CAS Registry No. 102052-95-9
ChEMBL Ligand CHEMBL154745
PubChem CID 73087
Search Google for chemical match using the InChIKey XNJHAZWZQGXOSC-FDNQDJDWSA-N
Search Google for chemicals with the same backbone XNJHAZWZQGXOSC
Search UniChem for chemical match using the InChIKey XNJHAZWZQGXOSC-FDNQDJDWSA-N
Search UniChem for chemicals with the same backbone XNJHAZWZQGXOSC
Comments
DZNep was originally identified as an inhibitor of S-adenosylhomocysteine (AdoHcy) hydrolase [1]. Subsequently DZNep has been reported to inhibit EZH2 histone methyltransferase activity [2].