DS-437

Ligand id: 8395

Name: DS-437

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 5
Rotatable bonds 9
Topological polar surface area 185.74
Molecular weight 397.15
XLogP -1
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-[2-[[(2S,3R,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]ethyl]-3-ethylurea
Synonyms
DS437
Database Links
PubChem CID 91827358
Search Google for chemical match using the InChIKey CACMCLIHCDTJHL-XLAISSFRSA-N
Search Google for chemicals with the same backbone CACMCLIHCDTJHL
Search UniChem for chemical match using the InChIKey CACMCLIHCDTJHL-XLAISSFRSA-N
Search UniChem for chemicals with the same backbone CACMCLIHCDTJHL
Comments
DS-437 is reported as a dual inhibitor of the protein arginine methyltransferases PRMT7 and PRMT5 [3].