pimavanserin

Ligand id: 8423

Name: pimavanserin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 44.81
Molecular weight 427.26
XLogP 5.03
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2016))
IUPAC Name
1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
International Nonproprietary Names
INN number INN
8877 pimavanserin
Synonyms
ACP 103 | ACP-103 | Nuplazid (proposed trade name)
Database Links
CAS Registry No. 706779-91-1
ChEMBL Ligand CHEMBL2111101
PubChem CID 10071196
Search Google for chemical match using the InChIKey RKEWSXXUOLRFBX-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey RKEWSXXUOLRFBX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RKEWSXXUOLRFBX
Wikipedia Pimavanserin
Comments
Pimavanserin is an inverse agonist of the serotonin 5-HT2A receptor [4]. Pharmaceutical formulations contain pimavanserin tartrate (PubChem CID 67017013) .