AZ20

Ligand id: 8477

Name: AZ20

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 96.56
Molecular weight 412.16
XLogP 2.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-3-methylmorpholine
Synonyms
AZ 20 | AZ-20 | compound 6 [PMID: 46244454]
Database Links
CAS Registry No. 1233339-22-4
ChEMBL Ligand CHEMBL2325697
PubChem CID 46244454
Search Google for chemical match using the InChIKey SCGCBAAYLFTIJU-CQSZACIVSA-N
Search Google for chemicals with the same backbone SCGCBAAYLFTIJU
Search UniChem for chemical match using the InChIKey SCGCBAAYLFTIJU-CQSZACIVSA-N
Search UniChem for chemicals with the same backbone SCGCBAAYLFTIJU
Comments
AZ20 is a novel potent and selective inhibitor the ATR serine/threonine kinase (ATR) [1].