AZD8186

Ligand id: 8527

Name: AZD8186

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 71.11
Molecular weight 457.18
XLogP 2.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(morpholin-4-yl)-4-oxo-4H-chromene-6-carboxamide
Synonyms
AZD 8186 | AZD-8186
Database Links
CAS Registry No. 1627494-13-6 (source: PubChem)
GtoPdb PubChem SID 252166729
PubChem CID 52913813
Search Google for chemical match using the InChIKey LMJFJIDLEAWOQJ-CQSZACIVSA-N
Search Google for chemicals with the same backbone LMJFJIDLEAWOQJ
Search UniChem for chemical match using the InChIKey LMJFJIDLEAWOQJ-CQSZACIVSA-N
Search UniChem for chemicals with the same backbone LMJFJIDLEAWOQJ
Comments
AZD8186 is a selective inhibitor of PI3Kβ- and δ-mediated AKT signalling [1].