angiopoietin-like 3   Click here for help

GtoPdb Ligand ID: 8716

Abbreviated name: ANGPTL3
Compound class: Endogenous peptide in human, mouse or rat
Comment: ANGPTL3 is prodominantly secreted in the liver, and has a pro-angiogenic function. The mature peptide is 444 amino acids long, and can be cleaved to form two functionally different sub-peptides: an N-terminal coiled-coil domain-containing chain (involved in lipid metabolism) and a C-terminal fibrinogen chain (angiogenic function).
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
ANGPTL3 angiopoietin like 3 Human angiopoietin-related protein 3 preproprotein angiopoietin 5, angiopoietin-like 3
Database Links Click here for help
CATH/Gene3D 3.90.215.10, 4.10.530.10
Ensembl Gene ENSG00000132855 (Hs)
GtoPdb PubChem SID 252827374
Human Protein Atlas ENSG00000132855 (Hs)
UniProtKB Q9Y5C1 (Hs)