compound 34 [PMID: 20189382]

Ligand id: 8743

Name: compound 34 [PMID: 20189382]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 123.38
Molecular weight 355.14
XLogP 3.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Database Links
ChEMBL Ligand CHEMBL1092820
PubChem CID 46830215
Search Google for chemical match using the InChIKey YKPDLYPZCGMXBO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YKPDLYPZCGMXBO
Search UniChem for chemical match using the InChIKey YKPDLYPZCGMXBO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YKPDLYPZCGMXBO
Comments
This is the most potent in vitro inhibitor of eukaryotic elongation factor 2 kinase (EEF2K) reported in [1].