CGS-27023A

Ligand id: 8846

Name: CGS-27023A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 117.21
Molecular weight 393.14
XLogP 1.86
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2R)-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methylbutanamide
Synonyms
CGS 27023A | CGS27023A | MMI270
Database Links
ChEMBL Ligand CHEMBL267178
PubChem CID 446504
RCSB PDB Ligand CGS
Search Google for chemical match using the InChIKey BSIZUMJRKYHEBR-QGZVFWFLSA-N
Search Google for chemicals with the same backbone BSIZUMJRKYHEBR
Search UniChem for chemical match using the InChIKey BSIZUMJRKYHEBR-QGZVFWFLSA-N
Search UniChem for chemicals with the same backbone BSIZUMJRKYHEBR
SynPHARM 82905 (in complex with MMP1)
Comments
CGS-27023A is reported as a potent pan-inhibitor of matrix metalloproteinases [2].
Note that CGS-27023A imay be used experimentally as the hydrochloride salt (PubChem CID 9888897).