cobalt protoporphyrin IX

Ligand id: 8902

Name: cobalt protoporphyrin IX

Abbreviated name: CoPP

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 100.38
Molecular weight 619.18
XLogP 3.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Synonyms
protoporphyrin IX containing Co
Database Links
DrugBank Ligand DB02110
PubChem CID 4972
Search Google for chemical match using the InChIKey AQTFKGDWFRRIHR-UHFFFAOYSA-L
Search Google for chemicals with the same backbone AQTFKGDWFRRIHR
Search UniChem for chemical match using the InChIKey AQTFKGDWFRRIHR-UHFFFAOYSA-L
Search UniChem for chemicals with the same backbone AQTFKGDWFRRIHR
SynPHARM 83076 (in complex with Rev-Erb-β)
Comments
CoPP is reported as an antagonist of the estrogen receptor β [1]. The PubChem identifier for protoporphyrin IX is CID 4971. This is a very similar structure to iron-bound heme, but with the ferrous ion replaced by a cobalt ion.