AZD8835

Ligand id: 8915

Name: AZD8835

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 161.97
Molecular weight 469.25
XLogP 0.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(4-{5-[5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-1-ethyl-1H-1,2,4-triazol-3-yl}piperidin-1-yl)-3-hydroxypropan-1-one
Synonyms
AZD 8835 | AZD-8835 | compound 25 [PMID: 26475521]
Database Links
GtoPdb PubChem SID 310264696
PubChem CID 76685059
Search Google for chemical match using the InChIKey ZGRDYKFVDCFJCZ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZGRDYKFVDCFJCZ
Search UniChem for chemical match using the InChIKey ZGRDYKFVDCFJCZ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZGRDYKFVDCFJCZ
Comments
AZD8835 is an inhibitor of the α and δ isoforms of phosphoinositide 3-kinase (PI3K) [1]. The compound's physical properties suggest it is suitable for oral administration.