megestrol

Ligand id: 9128

Name: megestrol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 54.37
Molecular weight 342.22
XLogP 3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1971))
IUPAC Name
(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
1529 megestrol
Synonyms
Chronopil | Magestin | Megace® | megestryl acetate
Database Links
CAS Registry No. 3562-63-8 (source: PubChem)
PubChem CID 19090
Search Google for chemical match using the InChIKey VXIMPSPISRVBPZ-NWUMPJBXSA-N
Search Google for chemicals with the same backbone VXIMPSPISRVBPZ
Search PubMed clinical trials megestrol
Search PubMed titles megestrol
Search PubMed titles/abstracts megestrol
Search UniChem for chemical match using the InChIKey VXIMPSPISRVBPZ-NWUMPJBXSA-N
Search UniChem for chemicals with the same backbone VXIMPSPISRVBPZ
Wikipedia Megestrol
Comments
Megestrol (commonly administered as the acetate ester: PubChem CID 11683) is a synthetic derivative of the female sex hormone progesterone. It has anti-estrogenic and antineoplastic activity.