esketamine

Ligand id: 9152

Name: esketamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 29.1
Molecular weight 237.09
XLogP 2.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2S)-2-(2-chlorophenyl)-2-methylaminocyclohexan-1-one
International Nonproprietary Names
INN number INN
7884 esketamine
Synonyms
(S)-Ketamine
Database Links
ChEMBL Ligand CHEMBL395091
PubChem CID 182137
Search Google for chemical match using the InChIKey YQEZLKZALYSWHR-ZDUSSCGKSA-N
Search Google for chemicals with the same backbone YQEZLKZALYSWHR
Search PubMed clinical trials esketamine
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Search UniChem for chemical match using the InChIKey YQEZLKZALYSWHR-ZDUSSCGKSA-N
Search UniChem for chemicals with the same backbone YQEZLKZALYSWHR
Wikipedia Esketamine
Comments
As the ketamine S enatiomer esketamine is twice as potent and has a more medically useful pharmacological action than the racemate ketamine racemate. Part of this advantage arises from inhibition of dopamine transporters.