BMS-986121

Ligand id: 9156

Name: BMS-986121

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 76.63
Molecular weight 365.99
XLogP 3.68
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
[(4-{2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4-yl}phenyl)(hydroxy)imino]-λ1-oxidanyl
Database Links
GtoPdb PubChem SID 315661240
PubChem CID 121231403
Search Google for chemical match using the InChIKey XUVKOFBHMYDXMJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XUVKOFBHMYDXMJ
Search UniChem for chemical match using the InChIKey XUVKOFBHMYDXMJ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XUVKOFBHMYDXMJ
Comments
BMS-986121 is a positive allosteric modulator (PAM) of the μ opioid receptor [3]. It is one of the compounds claimed in patent WO2014107344 [2]. BMS-986121 is built on a chemical scaffold representing a new chemotype for μ receptor PAMs [1].