DCC-2618

Ligand id: 9175

Name: DCC-2618

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 98.14
Molecular weight 489.16
XLogP 5.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-N'-[2,5-difluoro-4-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxyphenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide
Database Links
CAS Registry No. 1225278-16-9 (source: PubChem)
GtoPdb PubChem SID 315661258
PubChem CID 46208890
Search Google for chemical match using the InChIKey WWOXKWLDMLMYQY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WWOXKWLDMLMYQY
Search UniChem for chemical match using the InChIKey WWOXKWLDMLMYQY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WWOXKWLDMLMYQY
Comments
DCC-2618 is a preclinical pan-KIT kinase inhibitor being developed by Dicephera Pharmaceuticals for potential oncology use. It is claimed in patent WO2010051373 [1] as Example 39.