pizotifen

Ligand id: 93

Name: pizotifen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 31.48
Molecular weight 295.14
XLogP 5.17
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (UK (1998))
IUPAC Name
1-methyl-4-{6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene}piperidine
International Nonproprietary Names
INN number INN
2693 pizotifen
Synonyms
BC-105 | pizotifan | pizotyline | sandomigran
Database Links
BindingDB Ligand 82088
CAS Registry No. 73391-87-4
ChEBI CHEBI:50212
ChEMBL Ligand CHEMBL294951
PubChem CID 27400
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Wikipedia Pizotifen
Comments
Pizotifen is a benzocycloheptene-based anti-migraine drug, acting principally as an antagonist of serotonin 5-HT2A and 5-HT2C receptors.