BU72

Ligand id: 9363

Name: BU72

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 44.73
Molecular weight 428.25
XLogP 4.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Synonyms
compound 10 (Husbands and Lewis, 1995) [1]
Database Links
GtoPdb PubChem SID 328083465
PubChem CID 11487194
Search Google for chemical match using the InChIKey RGJHUVJQGAAZLK-NLYMFOMNSA-N
Search Google for chemicals with the same backbone RGJHUVJQGAAZLK
Search UniChem for chemical match using the InChIKey RGJHUVJQGAAZLK-NLYMFOMNSA-N
Search UniChem for chemicals with the same backbone RGJHUVJQGAAZLK
Comments
BU72 was reported as a long-lasting μ receptor agonist and a potential development lead for novel compounds effective for treating opioid dependence [2]. Strong lipophilic binding interactions with the μ receptor confer slow receptor kinetics, and therefore long duration of action.