ipragliflozin

Ligand id: 9394

Name: ipragliflozin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 118.39
Molecular weight 404.11
XLogP 3.57
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (Japan (2014))
IUPAC Name
(2S,3R,4R,5S,6R)-2-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
International Nonproprietary Names
INN number INN
9258 ipragliflozin
Synonyms
ASP-1941 | ASP1941 | Suglat®
Database Links
BindingDB Ligand 50381554
CAS Registry No. 761423-87-4
ChEMBL Ligand CHEMBL2018096
PubChem CID 10453870
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Comments
Ipragliflozin is a selective and orally available sodium/glucose cotransporter 2 (SGLT2; SLC5A2) inhibitor [2,4] (a 'gliflozin' family drug [1]) used to treat type 2 diabetes. In practice ipragliflozin is complexed with L-proline in a 1:1 ratio.